Introduction This information will help you understand your choices

Introduction
This information will help you understand your choices, whether you share in the decision-making process or rely on your doctor’s recommendation.

Key points in making your decision
Your decision about having allergy shots (immunotherapy) for allergies to insect stings will involve several issues regarding your current health and the likelihood that you might develop severe reactions to stings in the future. If your child is allergic to insect stings, these same factors will affect the decision about having allergy shots. Consider the following when making your decision:

If you have been stung in the past and had a systemic (whole-body) allergic reaction to the sting, you have a high risk of having a similar reaction if stung again.
If you had an anaphylactic (life-threatening) reaction in the past, immunotherapy significantly reduces your risk of having another severe systemic reaction from 60% to 3%.
You may not need allergy shots if you had a normal (localized) reaction or a large localized allergic reaction to an insect sting in the past. Only about 1% to 10% of people with localized reactions to insect stings progress to a more serious, systemic allergic reaction. 2
If you have taken allergy tests that identified one or more sensitivities to insect stings, immunotherapy can prevent life-threatening reactions and also reduce anxiety associated with insect stings.
Allergy shots may not be safe for you if you have an impaired immune system or certain kinds of heart problems.
Allergy shots are uncomfortable and costly, may trigger anaphylaxis in some people, and usually take 3 to 5 years to complete.
Medical Information


What are allergies to insect stings?
An allergic reaction to a sting occurs when your body’s immune system overreacts to substances called allergens in the venom of stinging insects such as bees, wasps, hornets, or fire ants.

What is a systemic allergic reaction?
Minor allergic reactions occur around the site of the sting (localized reaction) and can cause redness, swelling, fatigue, nausea, and a low fever. A more serious allergic reaction can spread throughout your entire body (systemic reaction) and cause symptoms such as itching, hives, and swelling of the tongue, throat, or other body parts. A life-threatening systemic allergic reaction called anaphylaxis can cause severe symptoms such as confusion, difficulty breathing, shock, and sometimes death.

What is immunotherapy for allergies to insect stings?
Standard immunotherapy is a series of allergy shots that can prevent or reduce the severity of symptoms during a systemic allergic reaction. Allergy shots are not needed if you have mild, local allergic reactions to insect stings.

Allergy shots work by introducing small amounts of insect venom into your body, making you less sensitive over time to the venom.

Once allergy tests have identified the insect(s) you are allergic to, you can begin immunotherapy. At first, you will receive weekly shots containing small doses of venom and allergens from the insect(s) that cause your allergies. After about 4 to 6 months of weekly shots, you will receive a maintenance dose every 4 weeks for another 4 to 6 months. Finally, you will continue getting monthly shots for 3 to 5 years, depending on the type of stings that cause your allergies; for example, fire ant allergies require longer treatment than other stinging insect allergies.

What is rush immunotherapy?
Accelerated or “rush” immunotherapy is done to rapidly increase your tolerance to an allergen. A series of shots is usually given every few hours on the same day or every few days. When the first injection is given, you must wait a period of time to see whether you have a reaction to the shot. If you do not, additional shots are given throughout the day. You (or your child) may have some anxiety about receiving the next injection; it may be helpful to bring a book or something to distract yourself while you wait for the next shot.

Maintenance is reached much more quickly with rush immunotherapy than standard immunotherapy—usually in 1 to 8 days instead of several months. Rush immunotherapy may be given if you have severe or life-threatening allergic reactions to insect stings, are a long distance from any type of health care facility, have severe allergic asthma, or are about to travel.

What are the risks of immunotherapy for allergies to insect stings?
Allergy shots are safe for most people. The most common side effects are redness and warmth at the injection site. Some people may experience large local reactions that include itching, hives, or swelling of the skin near the injection site.

However, allergy shots can trigger a more serious systemic reaction, which may include difficulty breathing or swelling in the deep layers of the skin. On rare occasions, a person may have a life-threatening allergic reaction (anaphylaxis) to the shots. Because of this possibility, the shots are given in a health care facility or other setting where emergency care can be provided if needed.

Talk with your health professional if you have an autoimmune disease (such as lupus) or are taking medications for heart problems (such as beta-blockers); allergy shots may not be safe for you.

If you need more information, see the topic Allergies to Insect Stings.

Your Information
Your choices are:

Get allergy shots to reduce your sensitivity to insect stings and reduce the risk of a severe allergic reaction (anaphylaxis).
Do not get allergy shots, and use other measures such as avoiding stinging insects and carrying an allergy kit to deal with the risk of a severe allergic reaction. Allergy shots usually are recommended only for people who have previously had a systemic reaction.
The decision about whether you or your child should have allergy shots (immunotherapy) for insect sting allergies takes into account your personal feelings and the medical facts.

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